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645 VENTURES MANAGEMENT, LLC

645 VENTURES MANAGEMENT, LLC is a Pre-seed, Seed, Series A, Series B and Series C+ fund in the US and Global writing $1M–$20M checks into Enterprise, Fintech, Healthcare, Marketplaces, commerce, software and web3.

Stages
Pre-seed, Seed, Series A, Series B, Series C+
Sectors
Enterprise, Fintech, Healthcare, Marketplaces, commerce, software, web3
Check size
$1M–$20M
Invests in
US-wide, Global
Actively investing
Yes
Founded
2013
Assets under management
$550M

Thesis

645 Ventures is an early-stage venture capital firm founded in 2013, with offices in New York City and San Francisco. The firm focuses on sectors such as SaaS, commerce, healthcare, and fintech, including vertical and horizontal SaaS, infrastructure software, online marketplaces, and Crypto/Web3. They apply investment themes like Citizen Professional, SaaS for the 2nd Wave, Engineering Value Chain Revolution, and Personalized Consumer. 645 Ventures primarily targets Seed, Series A, and Series B rounds, selectively considering pre-seed investments and providing follow-on capital. Their geographic focus is North America, but they also consider global opportunities. The firm typically leads or co-leads rounds, employing a concentrated portfolio strategy with 8-10 investments annually. They utilize a data-driven investment approach, leveraging proprietary software tools to identify and support transformative businesses. 645 Ventures manages approximately $550 million in assets under management across five funds.

Common questions

Does 645 VENTURES MANAGEMENT, LLC invest at the Pre-seed stage?

Yes. 645 VENTURES MANAGEMENT, LLC lists Pre-seed, Seed, Series A, Series B and Series C+ among the stages it invests in.

What check size does 645 VENTURES MANAGEMENT, LLC write?

645 VENTURES MANAGEMENT, LLC writes $1M–$20M checks.

Where does 645 VENTURES MANAGEMENT, LLC invest?

645 VENTURES MANAGEMENT, LLC invests in the US and Global.

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