APPLE TREE VENTURE MANAGEMENT LLC
APPLE TREE VENTURE MANAGEMENT LLC is a Seed, Series A, Series B and Series C+ fund in the US writing $25M–$100M checks into biotechnology, therapeutics, medical-devices and healthcare-services.
- Stages
- Seed, Series A, Series B, Series C+
- Sectors
- biotechnology, therapeutics, medical-devices, healthcare-services
- Check size
- $25M–$100M
- Invests in
- US-wide
- Actively investing
- Yes
- Founded
- 1999
- Assets under management
- $6.5B
Thesis
The firm's investment strategy exclusively targets biotechnology, therapeutics, medical devices, and healthcare services companies. ATP actively creates and invests in these companies, often starting with early-stage scientific ideas or spinouts. They provide flexible capital, strategic insights, and operational resources to foster research-driven enterprises. The investment stages covered range from seed, Series A, Series B, Series C, pre-IPO, to IPO, with a primary geographic focus on the United States. ATP employs a 'fewer-is-better' strategy, concentrating on a select portfolio of companies with strong scientific foundations and significant growth potential. Their approach is hands-on, actively assisting management teams through clinical trials, regulatory approvals, and market entry. The firm has reported Assets Under Management (AUM) of approximately $2.9 billion, with a fund valuation of $6.5 billion at the time of a Chapter 11 filing in December 2025. They have committed $2.9 billion and invested over $2.5 billion in approximately 45 biotechnology companies. Typical check sizes have historically ranged from $25 million in 2010 to over $50 million or $100 million more recently. The firm's headquarters are in New York, NY, with additional offices in San Francisco and Cambridge. A Chapter 11 bankruptcy filing by Apple Tree Life Sciences,
Common questions
Does APPLE TREE VENTURE MANAGEMENT LLC invest at the Seed stage?
Yes. APPLE TREE VENTURE MANAGEMENT LLC lists Seed, Series A, Series B and Series C+ among the stages it invests in.
What check size does APPLE TREE VENTURE MANAGEMENT LLC write?
APPLE TREE VENTURE MANAGEMENT LLC writes $25M–$100M checks.
Where does APPLE TREE VENTURE MANAGEMENT LLC invest?
APPLE TREE VENTURE MANAGEMENT LLC invests in the US.