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BREAKOUT MANAGEMENT, LLC

BREAKOUT MANAGEMENT, LLC is a Pre-seed, Seed and Series A fund in the US, UK, Japan, South Korea and China writing $1M–$10M checks into AI, Healthcare, biology, chemistry and computation.

Stages
Pre-seed, Seed, Series A
Sectors
AI, Healthcare, biology, chemistry, computation
Check size
$1M–$10M
Invests in
US-wide, UK, Japan, South Korea, China
Round role
Leads rounds
Actively investing
Yes
Founded
2016
Assets under management
$230M+

Thesis

Breakout Ventures, the venture capital arm of Breakout Management, LLC, is a science-focused investment firm that believes "the era of transformational science is here." They actively seek out and support early-stage companies (pre-seed, seed, Series A) at the intersection of biology, chemistry, computation, and artificial intelligence, aiming to accelerate the development of transformative solutions for human health and sustainability. Primarily focused on the United States, with some international interest, Breakout Ventures typically acts as a lead investor. Their strategy involves identifying "superhumans"—obsessed founders with deep technical expertise, world-class teams, and the ability to move with velocity. They are contrarian, backing companies that can achieve significant breakthroughs rapidly through lean teams, advanced data, and ruthless execution. The firm has a total AUM exceeding $230 million, with its largest fund, Fund III, closing in March 2026 with $114 million. Typical check sizes range from $1 million to $10 million, with an average check size of $20 million.

Common questions

Does BREAKOUT MANAGEMENT, LLC invest at the Pre-seed stage?

Yes. BREAKOUT MANAGEMENT, LLC lists Pre-seed, Seed and Series A among the stages it invests in.

What check size does BREAKOUT MANAGEMENT, LLC write?

BREAKOUT MANAGEMENT, LLC writes $1M–$10M checks.

Where does BREAKOUT MANAGEMENT, LLC invest?

BREAKOUT MANAGEMENT, LLC invests in the US, UK, Japan, South Korea and China.

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