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INTERSOUTH ADVISORS, INC.

INTERSOUTH ADVISORS, INC. is a Pre-seed, Seed, Series A, Series B and Series C+ fund in the US and Southeastern United States investing in Enterprise, Healthcare, technology, life-science, biotechnology, medical-devices, pharmaceuticals, genomics and life-sciences.

Not currently making new investments (as of August 9, 2026).

Stages
Pre-seed, Seed, Series A, Series B, Series C+
Sectors
Enterprise, Healthcare, technology, life-science, biotechnology, medical-devices, pharmaceuticals, genomics, life-sciences
Invests in
US-wide, Southeastern United States
Round role
Leads rounds
Actively investing
No
Founded
1985
Assets under management
$780M

Check size not disclosed

Thesis

Intersouth Partners is a venture capital firm founded in 1985, recognized as the oldest in North Carolina and one of the oldest in the Southeast. With $780 million in assets under management across seven partnerships, it is the largest VC fund in North Carolina. The firm historically focused on early-stage investments (pre-seed, seed, Series A, B, C) in the technology and life science sectors, primarily within North America and with a strong emphasis on the Southeastern United States. They have a history of leading and co-leading financing rounds.

Common questions

Does INTERSOUTH ADVISORS, INC. invest at the Pre-seed stage?

Yes. INTERSOUTH ADVISORS, INC. lists Pre-seed, Seed, Series A, Series B and Series C+ among the stages it invests in.

Where does INTERSOUTH ADVISORS, INC. invest?

INTERSOUTH ADVISORS, INC. invests in the US and Southeastern United States.