LIGHTSTONE VENTURES
LIGHTSTONE VENTURES is a Pre-seed, Seed, Series A, Series B and Series C+ fund in the US, Ireland, Canada and Israel writing $1M–$10M checks into biotechnology, medical-devices, therapeutics, central-nervous-system-disorders, immunology, oncology and ophthalmology.
- Stages
- Pre-seed, Seed, Series A, Series B, Series C+
- Sectors
- biotechnology, medical-devices, therapeutics, central-nervous-system-disorders, immunology, oncology, ophthalmology
- Check size
- $1M–$10M
- Invests in
- US-wide, Ireland, Canada, Israel
- Actively investing
- Yes
- Founded
- 2012
- Assets under management
- $732M
- Website
- lightstonevc.com
Thesis
Lightstone Ventures is a venture capital firm established in 2012, specializing in life sciences, particularly biotechnology and medical devices. Their thesis-driven strategy focuses on novel, disruptive technologies targeting central nervous system disorders, immunology, oncology, and ophthalmology. They invest across stages from pre-seed to growth equity, often leading or co-leading rounds, and provide strategic and operational support. The firm operates primarily in the US and Ireland, with additional investments in Canada and Israel. Their typical check size ranges from $1 million to $10 million. Lightstone Ventures has raised approximately $850 million across multiple funds, with their latest fund closing at $375 million in September 2021, and an AUM of $732 million as of February 2026. They emphasize empowering entrepreneurs to bring transformative treatments to patients and leverage data analytics and scientific platforms.
Common questions
Does LIGHTSTONE VENTURES invest at the Pre-seed stage?
Yes. LIGHTSTONE VENTURES lists Pre-seed, Seed, Series A, Series B and Series C+ among the stages it invests in.
What check size does LIGHTSTONE VENTURES write?
LIGHTSTONE VENTURES writes $1M–$10M checks.
Where does LIGHTSTONE VENTURES invest?
LIGHTSTONE VENTURES invests in the US, Ireland, Canada and Israel.