SOLEUS CAPITAL MANAGEMENT, L.P.

Thesis

Soleus Capital Management, L.P. is a private equity and hedge fund firm founded in 2018, based in Greenwich, Connecticut. The firm's investment thesis centers on achieving superior risk-adjusted returns through a fundamentals-driven strategy, primarily within the life sciences and broader healthcare sector. They focus on identifying and investing in innovative companies that are developing novel therapies, technologies, or healthcare delivery models to improve patient outcomes. Their strategy involves deep scientific and clinical expertise, rigorous due diligence on clinical data, regulatory pathways, competitive landscapes, and market potential. Soleus Capital invests across the healthcare lifecycle, from developmental-stage to commercial enterprises, with a preference for companies addressing significant unmet medical needs. Their investment scope includes biotechnology, medical technology (medtech), diagnostics, genomics, life science tools, and healthcare services. While primarily focused on public equities with a long/short strategy in U.S. and non-U.S. healthcare equities, they also engage in structured private investments and crossover rounds. Their private equity funds target middle-to-late stage investments, PIPES, and other illiquid securities like convertible equity and debt, often with an eye towards near-term IPOs. Additionally, they manage credit strategies focusing on loans, royalties, asset-backed securities, and other debt instruments from small- and mid-cap healthcare companies. The firm primarily focuses on opportunities within the United States but may consider select international investments. They generally lead investment rounds with a sweet spot check size of approximately $10 million, with investments ranging from $10 million to over $100 million. As of December 31, 2025, Soleus Capital managed approximately $3.66 billion in client assets.

Related lists

• Series C+ Healthcare investors
• Series C+ investors based in Greenwich, CT