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THE COLUMN GROUP

THE COLUMN GROUP is a Pre-seed, Seed, Series A, Series B and Series C+ fund in the US and Europe writing $20M–$60M checks into Healthcare, healthcare-tech, oncology, immunology, genetic-medicines and neuroscience.

Stages
Pre-seed, Seed, Series A, Series B, Series C+
Sectors
Healthcare, healthcare-tech, oncology, immunology, genetic-medicines, neuroscience
Check size
$20M–$60M
Invests in
US-wide, Europe
Round role
Leads rounds
Actively investing
Yes
Founded
2007
Assets under management
$4.2B

Thesis

The Column Group (TCG) is a San Francisco-based venture capital firm founded in 2007, specializing in early-stage drug discovery and development. With a science-driven approach, TCG aims to build fundamentally strong healthcare companies by leveraging unique scientific platforms and therapeutic potential. Their investment strategy focuses on companies with exceptional scientific foundations, prioritizing a select cohort with great ideas, world-class founders, and top-tier talent. TCG invests across pre-seed, seed, Series A, B, C, and D rounds, with a strong emphasis on Series A and B for platform biotechnology companies. While primarily focused on the United States, they also invest in companies emerging from European academic collaborations. TCG typically leads or co-leads investments, committing $20 million to $60 million in initial institutional rounds for platform biotech companies. Their sector focus includes oncology, immunology, genetic medicines, and neuroscience. The firm has significant assets under management, with reported figures around $4.2 billion across multiple private funds.

Common questions

Does THE COLUMN GROUP invest at the Pre-seed stage?

Yes. THE COLUMN GROUP lists Pre-seed, Seed, Series A, Series B and Series C+ among the stages it invests in.

What check size does THE COLUMN GROUP write?

THE COLUMN GROUP writes $20M–$60M checks.

Where does THE COLUMN GROUP invest?

THE COLUMN GROUP invests in the US and Europe.

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